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Chemical Knots - Periodic Table of Videos

Video vocabulary

complex

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US / 'kɒmpleks /

UK / kəmˈplɛks, ˈkɑmˌplɛks /

A2
  • adjecitve
  • Not being simple; having many parts or aspects
  • noun
  • Group of buildings all used for the same purpose
  • Psychological issue regarding self-image

pleased

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US / pliːzd /

UK / pliːzd /

A2
  • adjecitve
  • Being happy and satisfied
  • verb
  • To entertain someone, by dancing, singing etc.
  • To make someone happy by doing something

react

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US / rɪ'ækt /

UK / riˈækt /

A2
  • verb
  • To change when mixing with other chemicals
  • To behave or make a change in a particular way

any

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US / 'enɪ /

UK / ˈɛni /

A1
  • adjecitve
  • One, or some, no matter which
  • pronoun
  • One (thing) of many; some

come

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US / kʌm /

UK / kʌm /

A1
  • verb
  • To arrive at a place
  • (Of mail) to be delivered
  • To move toward someone; go with someone
  • To reach a certain point or state

think

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US / θɪŋk /

UK / θɪŋk /

A1
  • verb
  • To have an idea about something without certainty
  • To have an idea, opinion or belief about something

and

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US / ənd /

UK / ənd, ən,ænd /

A1
  • conjunction
  • Used to refer to two or more things
  • Plus; in addition; on top of that
  • Used to introduce an action that follows another

hope

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US / həʊp /

UK / hop /

A1
  • noun
  • When you wish something will happen; what you wish
  • verb
  • To expect and want something to happen

hopefully

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US / ˈhəʊpfəli /

UK / ˈhopfəli /

A2
  • adverb
  • In a manner wishing something to happen

guy

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US / ɡaɪ /

UK / ɡaɪ /

A1
  • noun
  • Man; boy; any person

lot

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US / lɒt /

UK / lɑt /

A1
  • noun
  • What happens to a person in life from chance; fate
  • A group of people seen together
  • Item for sale at an auction
  • Small area of land used for a purpose e.g. parking

synthesis

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US / ˈsɪnθəsɪs /

UK / ˈsɪnθɪsɪs /

B2
  • noun
  • Process of making something new out of other ones
  • Building something complex from simple parts

variety

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US / və'raɪətɪ /

UK / vəˈraɪɪti /

A2
  • noun
  • Particular type of thing or person

call

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US / kɔ:l /

UK / kɔl /

A1
  • noun
  • A order or request for action
  • The sound an animal makes, often when in danger
  • A correct prediction, e.g. a decision in a game
  • A short visit to a place or person
  • A decision by a referee or umpire in a game
  • verb
  • To make a request or order for action
  • (Animal) to make sounds to warn of danger
  • To announce the date of an election
  • To make a judgment about something
  • To give someone or something a name
  • To guess in advance the result or outcome
  • To visit a place or person for a short time
  • To phone someone
  • To speak, announce or shout in a loud voice

where

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US / hwɛə /

UK / hwɛr, wɛr /

A1
  • conjunction
  • At or in the place which
  • In whatever place
  • pronoun
  • Word you use to ask the location of something

flat

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US / flæt /

UK / flæt /

A2
  • adjecitve
  • Level; even; without curves or bumps
  • Lifeless; lacking energy or vitality
  • adverb
  • In a certain, direct or absolute manner
  • Against a surface without lifting or curving away
  • noun
  • Apartment; set of rooms for living in
  • The smooth or level part of something
  • Musical tone lower than another by a small degree
  • verb
  • To share an apartment with someone

enzyme

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US / ˈenzaɪm /

UK / ˈɛnzaɪm /

B2
  • noun
  • A protein made by cells

industry

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US / 'ɪndəstrɪ /

UK / ˈɪndəstri /

A1
  • noun
  • Hard work; being busy working
  • Factories or businesses that make certain products

most

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US / məʊst /

UK / most /

A1
  • adverb
  • Very; extremely
  • Greatest possible degree
  • pronoun
  • Nearly all of something

magic

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US / 'mædʒɪk /

UK / ˈmædʒɪk /

A2
  • adjecitve
  • Concerning or involving tricks for entertainment
  • Being able to produce good results or success
  • noun
  • Attractive, appealing, and exciting quality
  • Performance of tricks for entertainment
  • Special ability or skill that causes success
  • Use of the supernatural to make things happen

majority

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US / mə'dʒɒrətɪ /

UK / məˈdʒɔrɪti, -ˈdʒɑr- /

B1
  • noun
  • Amount that is more than half of a group

screen

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US / skri:n /

UK / skrin /

A2
  • noun
  • Wire net in a door or window to keep insects out
  • Displays in a theater on which movies are shown
  • Flat surface on a computer or TV showing images
  • verb
  • To hide or block something from being seen
  • To examine to find something, e.g. best candidate

couple

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US / 'kʌpl /

UK / ˈkʌpəl /

A2
  • noun
  • Two people in a romantic relationship
  • Two of something; two people; a pair
  • verb
  • To join something to something else
  • (Two animals) to engage in sexual relations
  • To put two people or things together

chemistry

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US / 'kemɪstrɪ /

UK / ˈkɛmɪstri /

B1
  • noun
  • The study of the structure of substances

linear

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US / ˈlɪniə(r) /

UK / ˈlɪniər /

B1
  • adjecitve
  • Made of lines
  • Series of progressing from one stage to another

name

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US / neɪm /

UK / nem /

A1
  • noun
  • What something or someone is called
  • verb
  • To state what someone is called, e.g. John

something

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US / ˈsʌmθɪŋ /

UK / ˈsʌmθɪŋ /

A1
  • adverb
  • In some degree or measure
  • noun
  • a person or thing of some value or consequence
  • pronoun
  • Thing that is not yet known or named
  • Approximately

along

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US / əˈlɒŋ /

UK / əˈlɔ:ŋ /

A1
  • adverb
  • As a companion; taken with someone
  • preposition
  • At a point on a line

anything

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US / ˈeniθɪŋ /

UK / ˈɛniˌθɪŋ /

A1
  • pronoun
  • A thing of any kind

from

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US / frəm /

UK / frʌm, frɑm,frəm /

A1
  • preposition
  • Starting at a particular place, time or level

form

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US / fɔ:m /

UK / fɔrm /

A1
  • noun
  • Sports team or person's current winning record
  • Document you complete when making an application
  • Visible shape or style; type; kind
  • verb
  • To organize something such as a club or group
  • To develop; to come into a shape or substance
  • To make something into a particular shape

condensation

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US / ˌkɒndenˈseɪʃn /

UK / ˌkɑ:ndenˈseɪʃn /

B2
  • noun
  • Act of shortening something
  • Drops of water on a surface, as produced by steam
  • Process by which a gas becomes a liquid

out

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US / aʊt /

UK / aʊt /

A1
  • adverb
  • No longer stylish (e.g. fashion)
  • Away from home, business, or the usual place
  • In a direction/movement away from inside or center
  • noun
  • Act when a batter cannot continue playing
  • verb
  • To tell people a secret

over

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US / 'əʊvə(r) /

UK / ˈovɚ /

A1
  • adverb
  • Finished; no longer happening
  • Towards the ground/away from a standing position
  • noun
  • A set of six consecutive balls bowled in cricket
  • other
  • Finished
  • preposition
  • Showing the relation when a thing is above another
  • On or covering something
  • Above or across something
  • More than you need
  • From one side to the other
  • In the direction of; toward

efficiency

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US / ɪˈfɪʃnsi /

UK / ɪˈfɪʃənsi /

A2
  • noun
  • Working well; producing something without waste

completely

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US / kəmˈpli:tli /

UK / kəmˈpliːtli /

A1
  • adverb
  • In every way or as much as possible

dimensionally

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US / /

UK / /

A1

illness

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US / ˈɪlnəs /

UK / ˈɪlnɪs /

A2
  • noun
  • Unhealthy condition of the mind or body

put

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US / pʊt /

UK / pʊt /

A1
  • phrasal verb
  • to make a light stop shining by pressing or moving a switch
  • verb
  • To move or place a thing in a particular position
  • To rate something in importance or value
  • To write or say something in a certain manner

two

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US / tu: /

UK / tu /

A1
  • number
  • 2

may

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US / meɪ /

UK / me /

A1
  • noun
  • 5th month of the year
  • other
  • Used to express a desire
  • Expresses permission, possibility or probability
  • Used to show that a thing could be true

this

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US / ðɪs /

UK / ðɪs /

A1
  • adjecitve
  • Used to indicate something already been discussed
  • Used to indicate something happening around now
  • adverb
  • An indication by a physical motion or gesture
  • A specific amount of
  • determiner
  • Person, thing, or idea near you
  • pronoun
  • Person, thing that has already been discussed

big

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US / bɪɡ /

UK / bɪɡ /

A1
  • adjecitve
  • Popular
  • Serious
  • Large

fit

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US / fɪt /

UK / fɪt /

A2
  • adjecitve
  • Good looking; physically attractive
  • Proper or acceptable; morally or socially correct
  • noun
  • Sudden loss of body control; attack (of crying)
  • verb
  • To install a machine, equipment etc.
  • To adjust or change to the right size or shape
  • To be the right size and shape that you want

glassware

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US / ˈɡlɑ:swɛə /

UK / ˈɡlæsˌwɛr /

C2
  • noun
  • Article of tableware made of glass

lead

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US / li:d /

UK / lid /

A1
  • adjecitve
  • Being the main part in movies or plays
  • noun
  • Wire for electricity, computer, etc.; cable
  • Information that could help to solve a crime
  • Main part in a play or movie
  • Heavy, gray metal element
  • Rope used to tie something to stop it escaping
  • Act of being at the front in a race or game
  • verb
  • To show the way or guide others
  • To be at the front of a race or game
  • To travel in front of; go in advance of others

little

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US / 'lɪtl /

UK / ˈlɪtl /

A1
  • adjecitve
  • Being short in length of time
  • Not great in size, amount, or degree; small
  • Being very young or younger than others
  • adverb
  • By an amount or degree that is not very much
  • Not often; rarely
  • noun
  • A person's name

natural

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US / ˈnætʃərəl /

UK / ˈnætʃərəl, ˈnætʃrəl /

A1
  • adjecitve
  • Being as one would expect; being usual or normal
  • Not made by humans; without human intervention

the

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US / ðə /

UK / ðə /

A1
  • article
  • Used to refer to something already mentioned
  • Used to show there is only one of something
  • determiner
  • Used to describe all of a family

also

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US / 'ɔ:lsəʊ /

UK / ˈɔlso /

A1
  • adverb
  • In addition; too; in a similar way

dock

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US / dɒk /

UK / dɑ:k /

B1
  • noun
  • Area in a harbor where boats arrive and are kept
  • verb
  • To take away a part of an animal's tail
  • To take away a part of someone's salary
  • To park a boat or ship in a harbor or marina

ester

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US / ˈestə(r) /

UK / ˈestər /

C1
  • noun
  • Compound of acid and alcohol with water taken out

how

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US / haʊ /

UK / haʊ /

A1
  • adjecitve
  • To what degree? in what amount?
  • adverb
  • (Used to explain the way to do something)
  • exclamation
  • For what purpose or reason?
  • (Used to ask someone or something's condition)

year

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US / jə: /

UK / jɪr /

A1
  • noun
  • Unit of time equal to 12 months or 365 or 366 days
  • Used to refer to the age of a person

you

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US / jʊ /

UK / ju /

A1
  • pronoun
  • Person someone is speaking or writing to
  • Person or people in general

cave

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US / keɪv /

UK / kev /

A2
  • noun
  • Large hole in the side of a cliff or hill
  • verb
  • To give in to pressure

chemical

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US / ˈkemɪkl /

UK / ˈkɛmɪkəl /

A2
  • adjecitve
  • Made of various elements
  • noun
  • Basic substance produced by mixing elements

candidate

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US / ˈkændɪdət /

UK / ˈkændɪˌdet, -dɪt /

B1
  • noun
  • Politician who is running for public office

definite

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US / ˈdefɪnət /

UK / ˈdɛfənɪt /

A2
  • adjecitve
  • Not likely to change; clearly decided

surprised

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US / səˈpraɪzd /

UK / sərˈpraɪzd /

A1
  • adjecitve
  • Feeling a shock when something unexpected happens
  • verb
  • To do something that another person didn't expect

complexity

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US / kəm'pleksətɪ /

UK / kəmˈplɛksɪti /

B1
  • noun
  • State of having many parts and not being simple

into

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US / 'ɪntə /

UK / ˈɪntu /

A1
  • preposition
  • Moving or going inside something
  • In the same direction as; in the direction of
  • So as to become; taking the state of

quote

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US / kwəʊt /

UK / kwot /

A2
  • noun
  • Written statement of the cost of something
  • The (often wise or famous) words of another person
  • verb
  • To tell someone how much a task will cost
  • To repeat precisely what a person said or wrote

one

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US / wʌn /

UK / wʌn /

A1
  • pronoun
  • You; we; people in general; someone
  • The thing or person previously referred to
  • adjecitve
  • Used to refer to people generally
  • Being a strong example of (something mentioned)
  • number
  • Number 1

than

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US / ðən /

UK / ðən /

A1
  • conjunction
  • Used to compare two things that are not equal

other

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US / 'ʌðə(r) /

UK / ˈʌðər /

A1
  • adjecitve
  • A thing different from that mentioned
  • determiner
  • (Something) else; not the first (one)
  • pronoun
  • Being the one and only thing of that category

turn

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US / tɜ:n /

UK / tɚn /

A1
  • noun
  • Place where changing of direction happens
  • Your time or chance to perform a duty
  • Your chance to play or do in say a game
  • Unexpected change, as in the weather
  • verb
  • To become (a particular age)
  • To become a different quality, color, etc.
  • To change the direction of something, e.g. a car
  • To move in an opposite direction or position
  • To shape metal with a spinning tool

term

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US / tɜ:m /

UK / tɚm /

A1
  • noun
  • Conditions applying to an agreement, contract
  • Length of time something is expected to happen
  • Fixed period of weeks for learning at school
  • The (precise) name given to something
  • verb
  • To call; give a name to

three

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US / θri: /

UK / θri /

A1
  • number
  • Number 3

finger

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US / ˈfɪŋgə(r) /

UK / ˈfɪŋɡɚ /

A1
  • noun
  • One of the five long parts of the hand
  • verb
  • To touch something with the ends of the hands
  • To identify the person guilty of a crime

imagination

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US / ɪˌmædʒɪˈneɪʃn /

UK / ɪˌmædʒəˈneʃən /

A2
  • noun
  • Ability to creates new ideas and mental images

less

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US / les /

UK / lɛs /

A1
  • adjecitve
  • Smaller in amount or degree
  • adverb
  • To a smaller degree
  • noun
  • A smaller amount
  • preposition
  • With the subtraction of

map

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US / mæp /

UK / mæp /

A1
  • noun
  • Diagram showing the geography of an area
  • verb
  • To draw a diagram to show the geography of an area
  • To find points of similarity between things

favourite

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US / ˈfeɪvərɪt /

UK / 'fevərɪt /

A1
  • adjecitve
  • Best liked or most enjoyed
  • noun
  • A thing that someone likes best or enjoys most

average

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US / 'ævərɪdʒ /

UK / ˈævərɪdʒ, ˈævrɪdʒ /

A2
  • adjecitve
  • Typical or normal; usual; ordinary
  • noun
  • Total of numbers divided by the number of items
  • verb
  • To add numbers then divide by the number of items

make

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US / meɪk /

UK / mek /

A1
  • noun
  • Product made by a particular company; brand
  • verb
  • To arrange or prepare something e.g. dinner
  • To get to (a place) on time
  • To gain the status of (teacher, lawyer, etc.)
  • To create something by putting things together
  • To earn a certain amount of money at a job
  • To cause or force a person to do something
  • To cause something to happen or be formed

treat

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US / tri:t /

UK / trit /

A1
  • noun
  • Something you buy for others as a surprise present
  • something that tastes good and that is not eaten often
  • verb
  • To pay for the food or enjoyment of someone else
  • To use medical methods to try to cure an illness
  • To act in a certain way toward someone

maybe

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US / ˈmeɪbi /

UK / ˈmebi /

A1
  • adverb
  • Possibly but not certainly; perhaps

not

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US / nɒt /

UK / nɑt /

A1
  • adverb
  • Word indicating the negative
  • (Used to form the negative of verbs)

quite

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US / kwaɪt /

UK / kwaɪt /

A1
  • adverb
  • Not very; fairly
  • Very; In a complete or total manner

our

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US / 'aʊə(r) /

UK / aʊr /

A1
  • determiner
  • Belonging to us

whole

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US / həul /

UK / hol /

A1
  • adjecitve
  • Complete or full; all of
  • Being in a good condition
  • noun
  • Complete amount or sum; total

knot

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US / nɒt /

UK / nɑ:t /

B1
  • noun
  • Secure form of tying a rope, string etc.
  • verb
  • To tie string, rope etc. firmly to stop it undoing

quotes

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US / kwəʊts /

UK / kwoʊts /

B1
  • other
  • Written statement of the cost of something
  • The (often wise or famous) words of people
  • verb
  • To tell someone how much a task will cost
  • To repeat precisely what a person said or wrote

surprise

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US / səˈpraɪz /

UK / sərˈpraɪz /

A1
  • adjecitve
  • That surprises you; not expected
  • noun
  • Something unexpected that slightly shocks you
  • verb
  • To do something that another person didn't expect

convert

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US / kən'vɜ:t /

UK / kənˈvɚt /

A2
  • noun
  • Person switching from one belief system to another
  • verb
  • To switch from a religion, belief etc. to another
  • To change form, character, or function to another

now

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US / naʊ /

UK / naʊ /

A1
  • adverb
  • At the present time or moment
  • Right away or in the next possible moment
  • Used to refer to something that just happened
  • Time between the present and a moment in the past
  • conjunction
  • Resulting from or because of something

structure

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US / ˈstrʌk.tʃə /

UK / ˈstrʌk.tʃɚ /

A2
  • noun
  • The way in which the parts of a system or object are arranged or organized, or a system arranged in
  • verb
  • To plan, organize, or arrange the parts of something

functionality

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US / ˌfʌŋkʃəˈnæləti /

UK / ˌfʌŋkʃəˈnælɪti /

A1
  • noun
  • Capable of serving a purpose well

want

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US / wɔnt /

UK / wɑnt, wɔnt /

A1
  • noun
  • Something you desire or wish for
  • State or condition of poverty
  • verb
  • To desire or wish for something; hope for a thing

unprecedented

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US / ʌnˈpresɪdentɪd /

UK / ʌnˈprɛsɪˌdɛntɪd /

B1
  • adjecitve
  • Not having happened before, or to such a degree

can

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US / kæn /

UK / kən,kæn /

A1
  • noun
  • A metal container for storing food
  • other
  • Able to; have the skill to; have the time to
  • verb
  • To have permission to
  • To be possible to do
  • To preserve food by sealing it in a metal container

excited

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US / ɪkˈsaɪtɪd /

UK / ɪkˈsaɪtɪd /

A2
  • adjecitve
  • Happy, interested or eager; enthusiastic
  • verb
  • To make something or someone become more active
  • To make someone feel happy, interested or eager

luck

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US / lʌk /

UK / lʌk /

A1
  • noun
  • Accidental way things happen, often good things

really

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US / ˈri:əli /

UK / ˈriəˌli, ˈrili /

A1
  • adverb
  • Used to stress something that is said; definitely
  • In a true or accurate manner
  • Very

study

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US / 'stʌdɪ /

UK / ˈstʌdi /

A1
  • noun
  • Room that a person studies or reads in
  • Piece of research
  • Topic or subject you research or learn about
  • verb
  • To focus on learning something usually at school

would

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US / wʊd /

UK / wʊd /

A1
  • other
  • Used to indicate something imagined
  • Used to ask or request something politely
  • Verb used to indicate possibility, request etc.
  • Used to indicate a preference
  • Used to indicate a reaction
  • Indicates something that occurred repeatedly
  • Used to indicate willingness or ability to do

attach

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US / ə'tætʃ /

UK / əˈtætʃ /

A2
  • verb
  • To be associated or connected with

disease

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US / dɪˈzi:z /

UK / dɪˈziz /

A2
  • noun
  • Illness that affects a person, animal, or plant

same

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US / seɪm /

UK / sem /

A1
  • adjecitve
  • Being equal in quality and amount
  • Identical; not different
  • Not changing; constant

tandem

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US / ˈtændəm /

UK / ˈtændəm /

C1
  • adverb
  • A bicycle with two sets of pedals and saddles

but

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US / bət /

UK / bʌt,bət /

A1
  • conjunction
  • Used before you say something different, opposite

good

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US / ɡʊd /

UK / ɡʊd /

A1
  • adjecitve
  • Proper, appropriate or right
  • (Of an amount) enough; plenty
  • Excellent; high quality
  • Acting well or properly; of moral character
  • In a positive or happy emotional state
  • noun
  • Advantage or benefit

research

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US / rɪ'sɜ:tʃ /

UK / rɪˈsɚtʃ, ˈriˌsɚtʃ /

A2
  • noun
  • Study done to discover new ideas and facts
  • Work done to find or discover knowledge
  • verb
  • To study in order to discover new ideas and facts

phrase

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US / freɪz /

UK / frez /

A2
  • noun
  • Common expression or saying
  • Section of musical notes in a piece of music
  • A set of words used together
  • verb
  • To choose words to say what you mean clearly

single

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US / 'sɪŋɡl /

UK / ˈsɪŋɡəl /

A1
  • adjecitve
  • Being one only, without others
  • Only; merely
  • Not married or in a relationship
  • noun
  • One run in cricket or a hit baseball
  • An individual song from a CD or album
  • Person who is not married or in a relationship

piece

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US / pi:s /

UK / pis /

A1
  • noun
  • A counter in a board game
  • Small part of something larger
  • verb
  • To put items together to assemble something

well

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US / wel /

UK / wɛl /

A1
  • adjecitve
  • Being in a fortunate, good condition or state
  • Healthy and in good condition
  • adverb
  • In an acceptable, proper, or successful manner
  • In a complete, total, or full manner
  • A great and considerable degree
  • In a successful way, in a good or satisfactory way
  • exclamation
  • Used to begin or continue a particular statement
  • Used to show you want to start saying something
  • Used to express that you are waiting for a reply
  • You say this to change the topic of a conversation
  • Used to indicate you are making a final remark
  • noun
  • Long deep hole in the ground to get water
  • verb
  • To cause your eyes to fill with tears

branch

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US / brɑ:ntʃ /

UK / bræntʃ /

A2
  • noun
  • Part of a family related to the same members
  • Part of organization with a specific function
  • Part of a tree growing outward from the trunk
  • One of several streams combining to create a river
  • Local office or store of a bank or large company
  • (Often secret) group or subgroup of a religion
  • Specific area of knowledge or study
  • verb
  • To separate away from the main part

computer

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US / kəmˈpju:tə(r) /

UK / kəmˈpjutɚ /

A1
  • noun
  • Machine for storing data, accessing the internet

per

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US / pə(r) /

UK / pɚ /

A2
  • preposition
  • In the manner directed or suggested
  • For each; during each

efficiently

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US / ɪ'fɪʃntlɪ /

UK / ɪˈfɪʃəntlɪ /

A2
  • adverb
  • In a way that does not create waste

few

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US / fju: /

UK / fju /

A1
  • pronoun
  • Not many, a small number

much

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US / mʌtʃ /

UK / mʌtʃ /

A1
  • adjecitve
  • Very; to a high level or degree
  • adverb
  • A lot; large amount; a high degree of
  • Nearly; basically
  • On many occasions; often
  • noun
  • A large amount; a great quantity

fact

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US / fækt /

UK / fækt /

A1
  • noun
  • Something that is known or proved to be true

depend

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US / dɪˈpend /

UK / dɪˈpend /

B1
  • verb
  • Be controlled or determined by (someone/something)

generate

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US / ˈdʒenəreɪt /

UK / ˈdʒɛnəˌret /

A2
  • verb
  • To create or be produced or bring into existence
  • To create electricity, heat, energy and power

question

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US / 'kwestʃən /

UK / ˈkwɛstʃən /

A1
  • noun
  • Issue or problems you are dealing with
  • What you ask about; issue
  • verb
  • To ask for or try to get information
  • To have or express concerns or uncertainty

wrap

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US / ræp /

UK / ræp /

B1
  • noun
  • Piece of clothing worn loosely on the shoulders
  • Thin bread filled with food and rolled
  • verb
  • To be or move around something
  • To cover something with paper or a cloth e.g. gift

load

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US / ləʊd /

UK / lod /

A2
  • noun
  • Large, often heavy, amount of a thing to be moved
  • A burden; heavy responsibility
  • Many or much of something; a lot of
  • Items that fill a truck, machine
  • verb
  • To put in items for use (e.g. bullets in a gun)

just

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US / dʒʌst /

UK / dʒʌst /

A1
  • adjecitve
  • Proper or appropriate; as is deserved
  • Doing or being what is right or fair
  • Legally correct; having enough evidence
  • adverb
  • Almost; nearly
  • Exactly at the time of
  • Exactly (the same as, like)

range

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US / reɪndʒ /

UK / rendʒ /

A2
  • noun
  • Cooking stove with multiple burners
  • Given distance from a point; how far plane can fly
  • Large grassy area where cattle wander and feed
  • Group or chain of mountains
  • Set of things with something in common
  • Limits within which something extends or varies
  • A set of products, e.g. so that people can choose
  • verb
  • To cover an area from one point to another
  • To extend to or vary within given limits
  • To put things in a row or in line
  • To wander or explore

occasionally

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US / əˈkeɪʒnəli /

UK / əˈkeɪʒən(ə)li /

A2
  • adverb
  • Not very often; sometimes; seldom

talk

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US / tɔ:k /

UK / tɔk /

A1
  • noun
  • Style of speaking
  • Discussion between two countries
  • Giving information in front of people; lecture
  • Saying things or ideas to someone with words
  • verb
  • To make a formal speech about something
  • To say things or ideas to someone with words

selectivity

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US / səˌlek'tɪvətɪ /

UK / sɪˌlɛkˈtɪvɪti, ˌsilɛk- /

B1
  • noun
  • Quality of being selective

difference

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US / 'dɪfrəns /

UK / ˈdɪfərəns, ˈdɪfrəns /

A1
  • noun
  • A thing or issue that people do not agree about
  • Not of the same kind; unlike other things

middle

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US / 'mɪdl /

UK / ˈmidl /

A1
  • adjecitve
  • Equal distance from extremes
  • noun
  • Place that is halfway between two things

never

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US / 'nevə(r) /

UK / ˈnɛvɚ /

A1
  • adverb
  • Not ever; not at any time

success

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US / sək'ses /

UK / səkˈsɛs /

A2
  • noun
  • Achievement of a desired purpose or goal
  • A successful person; one who achieved their aims

send

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US / send /

UK / sɛnd /

A1
  • verb
  • To cause to behave or respond in a particular way
  • To cause mail or packages to go to another place
  • To move something quickly in a particular way
  • To give information or greetings to someone

serendipity

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US / ˌserən'dɪpətɪ /

UK / ˌsɛrənˈdɪpɪti /

C1
  • noun
  • Good luck in making unexpected/fortunate discovery

analogy

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US / əˈnælədʒi /

UK / əˈnælədʒi /

B1
  • noun
  • Comparison of things based on their similarity

compound

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US / 'kɒmpaʊnd /

UK / kɑmˈpaUnd /

B1
  • adjecitve
  • (Of a term) created by combining two or more words
  • noun
  • Series of buildings that are walled or fenced off
  • Chemical made up of several others
  • Closed walled area, as in a prison
  • Something formed by combining elements/parts
  • Term created by using two or more words together
  • verb
  • To pay interest on a loan including the interest
  • To make something from various parts or components
  • To make a mistake or problem worse

for

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US / fə(r) /

UK / fɔr,fə /

A1
  • preposition
  • Used to show the purpose, or need of something

through

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US / θru: /

UK / θru /

A2
  • adjecitve
  • having finished using or doing something
  • adverb
  • From the beginning of something until the end
  • preposition
  • Over, in, across an entire thing or place
  • Allowing you to pass between, or to
  • By a particular way or process; by the use of

time

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US / taɪm /

UK / taɪm /

A1
  • noun
  • Speed at which music is played; tempo
  • Point as shown on a clock, e.g. 3 p.m
  • Number of hours, minutes needed to do something
  • Occasion when something happens
  • Period or occasion that something occurred
  • Period in history or the past
  • Something measured in minutes, hours, days, etc.
  • How long an event takes; duration
  • verb
  • To check speed at which music is performed
  • To choose a specific moment to do something
  • To measure how long an event takes, e.g. a race
  • To schedule something to occur at a specific moment

define

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US / dɪ'faɪn /

UK / dɪˈfaɪn /

A2
  • verb
  • To explain the meaning of words
  • To set or mark the limits of something

generation

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US / ˌdʒenəˈreɪʃn /

UK / ˌdʒɛnəˈreʃən /

A2
  • noun
  • Act or process of producing or causing something
  • People born and living at about the same time

light

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US / laɪt /

UK / laɪt /

A1
  • adjecitve
  • Being bright making it easy to see; not dark
  • Being pale and lacking darkness of color
  • Not heavy; weighing only a little
  • adverb
  • Carrying few bags when traveling
  • noun
  • A source of energy that makes a room or area bright
  • Way in which something or someone is understood
  • verb
  • To cause something to burn; put a burning match to
  • To provide a way to see ahead

molecule

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US / ˈmɒlɪkju:l /

UK / ˈmɑlɪˌkjul /

B2
  • noun
  • Two or more atoms chemically combined

scaffold

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US / 'skæfəʊld /

UK / ˈskæfəld, -ˌold /

C2
  • noun
  • Temporary supporting platform outside buildings
  • verb
  • To build on previous information or knowledge

those

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US / ðəʊz /

UK / ðoz /

A1
  • determiner
  • The people or things we are talking about
  • pronoun
  • The objects far from the speaker

though

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US / ðəu /

UK / ðo /

A1
  • adverb
  • Although, despite the fact that

feature

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US / 'fi:tʃə(r) /

UK / ˈfitʃɚ /

A2
  • adjecitve
  • Main; important
  • noun
  • Special report in a magazine or paper
  • Distinctive or important point of something
  • verb
  • To highlight or give special importance to

fill

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US / fɪl /

UK / fɪl /

A1
  • noun
  • Act of filling; amount used to make something full
  • verb
  • To make something full
  • To move into all parts of an area
  • To repair a surface by adding a substance to it
  • To use (time); to do something during

intricate

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US / ˈɪntrɪkət /

UK / ˈɪntrɪkɪt /

B2
  • adjecitve
  • Very detailed or difficult to untangle

string

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US / strɪŋ /

UK / strɪŋ /

A2
  • noun
  • A line of connected objects
  • Thick thread; thin rope
  • verb
  • To tie or connect things together with a thread

work

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US / wɜ:k /

UK / wɚk /

A1
  • adjecitve
  • Activity completed in order to make money
  • noun
  • The product of some artistic or literary endeavor
  • Everything created by an author, artist, musician
  • Activity you do in order to make money
  • Place of employment
  • Final product or result of a some labor or effort
  • verb
  • To bring into a specific state of success
  • To be functioning properly, e.g. a car
  • To do your job in your company or workplace
  • To make an effort to do something
  • To operate a machine or device

amine

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US / ə'mi:n /

UK / ə'mi:n /

C2
  • noun
  • Compound of ammonia containing nitrogen

all

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US / ɔ:l /

UK / ɔl /

A1
  • adverb
  • Completely; totally
  • determiner
  • Being every one of something
  • pronoun
  • 100% of something; the complete amount

drop

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US / drɒp /

UK / drɑp /

A1
  • noun
  • Distance between a higher and a lower level
  • Act of letting something fall (from your hand)
  • A decrease in quantity or quality; reduction
  • Tiny amount of liquid, with rounded bottom
  • verb
  • To drive someone to a place and then drive away
  • To let something fall from your hand
  • To fall or lie down quickly, as when shot
  • To decide to stop something e.g. a course)
  • To (cause to) reduce in quantity or quality

produce

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US / prə'dju:s /

UK / prəˈdus, -ˈdjus, pro- /

A1
  • noun
  • Fresh foods such as fruits and vegetables
  • verb
  • To grow something naturally
  • To make something appear
  • To manufacture something using machines
  • To control the making a movie or television show

receptor

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US / rɪˈseptə(r) /

UK / rɪˈseptər /

B2
  • noun
  • A nerve ending that changes stimuli into impulses

who

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US / hu: /

UK / hu /

A1
  • pronoun
  • Which person
  • Used to introduce information about people

figure

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US / ˈfiɡə /

UK / ˈfɪɡjɚ /

A1
  • noun
  • Your body shape
  • Numbers in a calculation
  • Doll-like thing meant to represent a person
  • Picture or diagram giving information in a text
  • Person who is very important or famous
  • Shape of a person seen indistinctly or in outline
  • Amount that is expressed in numbers
  • verb
  • To appear in a game, play or event
  • To calculate how much something will cost
  • To understand after thinking; work out

design

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US / dɪˈzaɪn /

UK / dɪˈzaɪn /

A1
  • noun
  • The way something is planned, to fulfill a purpose
  • verb
  • To plan in a particular way to fulfill a purpose
  • To think of a plan

huge

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US / hju:dʒ /

UK / hjudʒ /

A2
  • adjecitve
  • Very very large

useful

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US / ˈju:sfl /

UK / ˈjusfəl /

A1
  • adjecitve
  • That can help with a particular task

way

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US / weɪ /

UK / we /

A1
  • adverb
  • Used to emphasize the amount of something
  • noun
  • Particular aspect of something being thought about
  • One of various choices that could be made
  • Particular existing condition or state
  • (Often long) distance or length of time
  • How something is done
  • Route to go to a place
  • Small street
  • Usual behavior, emotions or habits of someone

pretty

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US / 'prɪtɪ /

UK / ˈprɪti /

A1
  • adjecitve
  • Being attractive to the eye in a simple way
  • adverb
  • Very; to a great degree

sedative

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US / ˈsedətɪv /

UK / ˈsɛdətɪv /

B2
  • noun
  • Drugs administered to reduce anxiety or excitement

paper

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US / ˈpeɪpə(r) /

UK / ˈpeɪpər /

A1
  • adjecitve
  • Not existing in reality, or done infrequently
  • Made from the material that we use to make books
  • noun
  • Academic writing or a talk on a specific topic
  • Written test
  • Newspaper
  • Pages of a book are made from this

change

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US / tʃeɪndʒ /

UK / tʃendʒ /

A1
  • noun
  • Exchange of one set of clothes for another
  • Money in the form of coins instead of paper
  • Money returned after giving too much
  • Act of making or becoming something else
  • verb
  • To exchange one set of clothes for another
  • To exchange one kind of money for another
  • To replace something with another thing
  • To make or become something else
  • To go from one train, bus, etc. and go to another

functional

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US / ˈfʌŋkʃənl /

UK / ˈfʌŋkʃənəl /

A2
  • adjecitve
  • Useful; not just for decoration

hold

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US / həʊld /

UK / hold /

A1
  • noun
  • Section of a ship or plane used for storing things
  • Influence or power held over someone
  • Place of support for hands or feet when climbing
  • verb
  • To agree to keep something for someone
  • To have the capacity to support/contain something
  • To control an area and protect it from attack
  • To not allow someone to leave a place
  • To cause an event to happen at a place or time
  • To use hands or arms to carry or keep something
  • To have a specific quality or property
  • To keep an image, belief or feeling in your mind
  • To have or own something
  • To wait before being able to talk on the phone
  • To limit the movement of someone in a sport

pathway

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US / ˈpɑ:θweɪ /

UK / ˈpæθˌwe, ˈpɑθ- /

B1
  • noun
  • A path or way that you can walk

simple

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US / 'sɪmpl /

UK / ˈsɪmpəl /

A1
  • adjecitve
  • Not hard to understand or do; not complex
  • Having only a few parts; not complex
  • Being ordinary or normal
  • Being plain; without a lot added for style

space

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US / speɪs /

UK / spes /

A1
  • noun
  • Empty area kept for a specific reason, like a car
  • Empty area with nothing in it
  • Area in the sky where the stars are
  • Area between written words on a page
  • verb
  • To make a certain distance or time between

show

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US / ʃəʊ /

UK / ʃo /

A1
  • noun
  • False display of love, emotion or action
  • An event for displaying or promoting goods
  • Play, opera or theater production
  • Presentation that is broadcast on TV or radio
  • verb
  • To be easily seen or displayed
  • To display your emotions or feelings
  • To let someone see something; display
  • To explain or teach how something is done
  • To lead someone somewhere; point them to something
  • To prove something to be true, correct
  • To reveal or allow something to be seen

bit

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US / bɪt /

UK / bɪt /

A1
  • noun
  • Device put in a horse's mouth to control it
  • Small piece of something
  • verb
  • (E.g. of fish) to take bait and be caught

encourage

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US / ɪn'kʌrɪdʒ /

UK / ɛnˈkɚrɪdʒ, -ˈkʌr- /

A2
  • verb
  • To increase the chance of something happening
  • To make someone more determined or confident

look

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US / lʊk /

UK / lʊk /

A1
  • noun
  • Person's beauty or physical attractiveness
  • Particular style of dress, clothes, or appearance
  • The way someone, something appears to be
  • Act of searching for or examining something
  • verb
  • To appear to be; seem

between

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US / bɪˈtwi:n /

UK / bɪˈtwin /

A1
  • preposition
  • From one person, thing, or place, to another
  • In the space that separates two objects
  • Among two or more people who share something

everything

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US / 'evrɪθɪŋ /

UK / ˈɛvriˌθɪŋ /

A1
  • pronoun
  • All of the things mentioned

they

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US / ðeɪ /

UK / ðe /

A1
  • pronoun
  • Two or more people, animals, or things

very

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US / 'verɪ /

UK / ˈvɛri /

A1
  • adjecitve
  • Concerning a large degree or amount
  • adverb
  • A lot; much; many
  • Used to stress or emphasize a noun

crystallography

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US / ˌkrɪstəˈlɒɡrəfi /

UK / ˌkrɪstəˈlɑːɡrəfi /

A1
  • noun
  • Science that studies crystals

project

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US / prəˈdʒekt /

UK / prəˈdʒɛkt /

A1
  • noun
  • A planned piece of work for specific purpose
  • Group of homes built by government for poor people
  • verb
  • To predict what will happen in the future
  • To show something on a screen using light
  • To stick out past the edge of something

take

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US / teɪk /

UK / tek /

A1
  • noun
  • Filming of a single scene for TV or the movies
  • verb
  • To accept something that is offered
  • To use a method of traveling, e.g. a bus or train
  • To use a camera to make (a photo)
  • To pick up something and go away with it
  • To study a subject in school
  • To attempt to pass (an exam)
  • To require a certain amount of time, money, space

tie

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US / taɪ /

UK / taɪ /

A2
  • noun
  • Item, such as string or wire, used to join things
  • Strong connection between people, countries
  • When both sides in a game, vote get same score
  • One match or game that is part of a bigger contest
  • Something that lessens a person's freedom
  • Thin piece of cloth worn round neck of shirt
  • Piece of wood/metal used to stop something moving
  • verb
  • To attach things (together) with a string or rope
  • To end a game, contest or vote with the same score
  • To require someone to be in a specific place

creativity

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US / ˌkri:eɪ'tɪvətɪ /

UK / ˌkrieˈtɪvətɪ /

A2
  • noun
  • Ability to imagine new ideas

last

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US / lɑ:st /

UK / læst /

A1
  • adjecitve
  • Most recent; the latest
  • The one before
  • adverb
  • Final; with nothing following; after all others
  • Most recent; the latest
  • determiner
  • The one at the end
  • verb
  • To remain or continue for a certain period of time

have

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US / həv /

UK / hæv /

A1
  • verb
  • To drink, smoke, eat or use something
  • To experience the effects of something
  • To organize an event, or join in an activity
  • To own, possess, or hold something
  • To cause to happen or produce a particular effect

plan

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US / plæn /

UK / plæn /

A1
  • noun
  • Drawing of how something should be done or made

part

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US / pɑ:t /

UK / pɑ:rt /

A1
  • adjecitve
  • To some degree; half; not fully
  • noun
  • Division of a book
  • Ratio of something, e.g. 3 of gin, 1 of tonic
  • A line in a person's hair, made with a comb
  • Character an actor plays on stage, movie, or TV
  • Some, but not all of a specific thing
  • Role in causing something to happen
  • verb
  • To make a line in a person's hair, by using a comb
  • To move two things apart creating a space
  • To leave someone, or to break off a relationship

diethyl

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US / vɜ:ˈbəʊs /

UK / vɜ:rˈboʊs /

A1

ketone

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US / ˈkiːtəʊn /

UK / ˈkiton /

A1
  • noun
  • Any of a class of organic compounds having a carbonyl group linked to a carbon atom in each of two h

with

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US / wɪð /

UK / wɪð, wɪθ /

A1
  • preposition
  • As an employee of a certain company
  • Against something or someone
  • By using something as a means
  • Due to; because of
  • Including
  • Possessing as a feature
  • Related to
  • (Of the manner/attitude by which you do something)
  • Used to express that people or things are together

via

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US / ˈvaɪə /

UK / ˈvaɪə, ˈviə /

B1
  • preposition
  • By the means of using something
  • By going through, by way of

active

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US / ˈæktɪv /

UK / ˈæktɪv /

A1
  • adjecitve
  • Moving around a lot or doing many things

see

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US / si: /

UK / si /

A1
  • verb
  • To go on a date with someone
  • To predict whether something is, or will be true
  • To understand what someone says
  • To use your eyes to look at something
  • To visit a place often for sightseeing or pleasure
  • To visit or meet with someone
  • To find out by waiting or looking
  • To watch (a game, movie or TV show)

could

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US / kəd /

UK / kʊd /

A1
  • other
  • Past form of 'can' to mean have ability
  • Used to ask for something politely, or to offer

complete

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US / kəm'pli:t /

UK / kəmˈplit /

A1
  • adjecitve
  • Being finished; done; achieved
  • Being as perfect and as total as could be
  • verb
  • To finish or reach the end of doing something

handle

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US / 'hændl /

UK / ˈhændl /

A2
  • noun
  • The part of a door you hold to open it
  • Thing you hold to carry or open a bag, pan etc.
  • verb
  • To cope with or take responsibility for
  • To control a machine, car etc.
  • To control or be controlled /used in a certain way
  • To deal with a particular situation/person; manage
  • To buy, sell, or move materials or goods
  • To hold, control, or use something with the hands
  • To touch objects with the hands to look at them

moment

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US / 'məʊmənt /

UK / 'moʊmənt /

A1
  • noun
  • Very short or brief period of time
  • A particular period in time

slightly

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US / ˈslaɪtli /

UK / ˈslaɪtli /

B1
  • adverb
  • Only a little

away

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US / ə'weɪ /

UK / əˈwe /

A1
  • adjecitve
  • Not present
  • adverb
  • Disappear completely
  • Doing something with a lot of energy
  • Not here; far from here; in a different direction
  • To a different area, location

group

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US / ɡru:p /

UK / ɡrup /

A1
  • noun
  • Two or more musicians who play music together
  • Number of people or things gathered together
  • verb
  • To combine or collect objects or people together

traditionally

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US / trə'dɪʃənəlɪ /

UK / trə'dɪʃənəlɪ /

B2
  • adverb
  • Something done in a customary, traditional manner

world

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US / wɜ:ld /

UK / wɜrld /

A1
  • noun
  • All the humans, events, activities on the earth
  • Political division due to some kind of similarity

mouthful

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US / ˈmaʊθfʊl /

UK / ˈmaʊθˌfʊl /

A2
  • noun
  • Something difficult to pronounce
  • Amount of food a mouth will hold at one time

end

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US / end /

UK / ɛnd /

A1
  • noun
  • The point where a process or activity stops
  • A point that marks the limit of something; finish
  • Goal or desired result
  • The tip, edge or limit of something
  • verb
  • To be the last part of something

discovery

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US / dɪ'skʌvərɪ /

UK / dɪˈskʌvəri /

A2
  • noun
  • Learning something for the first time

sample

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US / ˈsɑ:mpl /

UK / ˈsæmpl /

A2
  • noun
  • A small quantity of something used as a taster
  • verb
  • To try (e.g. food, drink), to see if you like it

here

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US / hɪə(r) /

UK / hɪr /

A1
  • adverb
  • In this place; at this location, position or time

new

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US / nju: /

UK / nu, nju /

A1
  • adjecitve
  • Not old, recently born, built or made
  • Being or doing something for the first time
  • Not felt, seen or known previously
  • Having been recently bought or obtained

scientific

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US / ˌsaɪənˈtɪfɪk /

UK / ˌsaɪənˈtɪfɪk /

A2
  • adjecitve
  • Concerning academic study of the physical world

try

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US / traɪ /

UK / traɪ /

A1
  • noun
  • Act of putting the ball over the rugby goal line
  • verb
  • To make an effort, to attempt to do something
  • To examine someone or something in a court of law
  • To test to see if it is good or you like it
  • To make a person go through hardship; test
  • To examine something to see if it works

carbon

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US / 'kɑ:bən /

UK / ˈkɑrbən /

B1
  • noun
  • Chemical element with an atomic number of 6

jazz

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US / dʒæz /

UK / dʒæz /

A2
  • noun
  • Music known for its energetic beat and spontaneity
  • Empty or meaningless talk, conversation

reason

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US / 'ri:zn /

UK / ˈrizən /

A1
  • noun
  • Ability to think about facts and form a judgment
  • Explanation for why something occurred or was done
  • verb
  • To think and make conclusions in a logical manner

side

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US / saɪd /

UK / saɪd /

A1
  • adjecitve
  • In addition to the central or most important thing
  • Next to, or very close to, the right or left of
  • noun
  • Position or opinion that is opposite to another
  • Right or left part of a person's body
  • Feature of someone's personality
  • Straight edge of an object
  • One of two or more groups fighting each other
  • verb
  • To decide to agree with one point, not the other

agent

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US / 'eɪdʒənt /

UK / ˈedʒənt /

A2
  • noun
  • Chemical with the power to make chemical reactions
  • Person who represents or decides for others
  • A spy; someone who spies on other countries

certain

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US / ˈsə:tn /

UK / ˈsɚtn /

A1
  • adjecitve
  • Definite, fixed
  • Referring to an unspecified amount or quantity
  • Being sure about something; without doubt

explain

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US / ɪk'spleɪn /

UK / ɪkˈsplen /

A1
  • verb
  • To make clear or easy to understand by describing

always

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US / 'ɔ:lweɪz /

UK / ˈɔlwez,-wɪz,-wiz /

A1
  • adverb
  • For a very long time
  • At all times; in every situation
  • For ever

drug

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US / drʌɡ /

UK / drʌɡ /

A2
  • noun
  • Illegal substance taken for effect on the mind
  • Chemical used as a medicine
  • verb
  • To give drugs to someone to make them sleep

itself

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US / ɪtˈself /

UK / ɪtˈsɛlf /

A1
  • pronoun
  • Referring to it

many

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US / 'menɪ /

UK / ˈmɛni /

A1
  • determiner
  • Used to refer a large number of things

musician

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US / mjuˈzɪʃn /

UK / mjuˈzɪʃən /

A1
  • noun
  • Person who writes, sings, or plays music, as a job

complicated

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US / 'kɒmplɪkeɪtɪd /

UK / ˈkɑmplɪˌketɪd /

B1
  • adjecitve
  • Difficult to do, understand or use
  • verb
  • To make more difficult to do, understand or use

precursor

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US / pri:ˈkɜ:sə(r) /

UK / pri:ˈkɜ:rsə(r) /

B1
  • noun
  • Something that comes before another; forerunner

actually

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US / ˈæktʃuəli /

UK / ˈæktʃuəli /

A1
  • adverb
  • Used to add new (often different) information

bond

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US / bɒnd /

UK / bɑnd /

A2
  • noun
  • Rope, chain or other thing used to tie someone up
  • Closeness that is shared between people or groups
  • Loan that a government must buy back by a set date
  • Written agreement to pay back borrowed money
  • Joint or connection, often using glue
  • verb
  • To develop a close relationship with
  • To become joined or connected, e.g. using glue

oxidation

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US / ˌɒksɪ'deɪʃn /

UK / ˌɑksɪˈdeʃən /

C1
  • noun
  • Process of combining with oxygen

use

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US / ju:s /

UK / ju:s /

A1
  • noun
  • Ability to employ something
  • Need to enable it to work
  • Permission to do something with something
  • Act of spending money
  • Operation of a machine for its function
  • verb
  • To have; to eat, drink, consume etc.
  • To need to operate or work
  • To operate a machine, e.g. a computer
  • To treat a person badly
  • To do something with, for a task or purpose

smallish

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US / ˈsmɔ:lɪʃ /

UK / ˈsmɔːlɪʃ /

A2
  • adjecitve
  • Rather small

breakthrough

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US / 'breɪkθru: /

UK / ˈbrekˌθru /

B2
  • noun
  • Important discovery in doing something difficult

four

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US / fɔ:(r) /

UK / fɔr, for /

A1
  • number
  • 4

inside

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US / ˌɪn'saɪd /

UK / ɪnˈsaɪd, ˈɪnˌsaɪd /

A2
  • adjecitve
  • Being in something
  • Being in a building
  • adverb
  • Into a house; indoors
  • noun
  • Inner part or surface of something

obviously

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US / ˈɒbviəsli /

UK / ˈɑːbviəsli /

A2
  • adverb
  • In a way that is obvious/easy to see or understand

occasional

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US / əˈkeɪʒənl /

UK / əˈkeʒənəl /

A2
  • adjecitve
  • Not happening often; irregular; rare

colour

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US / ˈkʌlə(r) /

UK / ˈkʌlɚ /

A1
  • noun
  • Quality of things you can see, e.g. red, blue
  • Pink or red in your face, e.g. after being ill
  • The shade of someone's skin e.g. black, or yellow
  • verb
  • To change or affect someone's opinion
  • To make something colorful using colored pencils

pharmaceutical

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US / ˌfɑ:məˈsu:tɪkl /

UK / ˌfɑ:rməˈsu:tɪkl /

B2
  • adjecitve
  • Concerning the science of drugs and medicines

then

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US / ðen /

UK / ðɛn /

A1
  • adverb
  • A time that is not now
  • Following another thing in time or arrangement
  • Following on reasonably from what was just stated
  • At that time, not now

step

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US / step /

UK / stɛp /

A1
  • noun
  • Movement done as part of a particular dance
  • Distance covered by one movement of a leg; stride
  • One part or stage in a process
  • Sound made by the feet while walking; footstep
  • Flat horizontal piece that forms stairs
  • verb
  • To raise and moving the foot to put it down

alkene

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US / ˈælkiːn /

UK / ˈælkiːn /

A1
  • other
  • Any unsaturated aliphatic hydrocarbon

first

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US / fɜ:st /

UK / fɚst /

A1
  • adjecitve
  • 1st; Coming before all others in time or place
  • noun
  • Something that has not happened before
  • Position of the winner of a competition

get

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US / ɡet /

UK / ɡɛt /

A1
  • verb
  • To become affected by illness or disease
  • To begin to feel or understand an emotion or idea
  • To send or bring someone or something home, etc.
  • To go somewhere to obtain something
  • To (cause to) do a particular thing
  • To obtain, receive or be given something
  • To currently have
  • To prepare for use
  • To understand something being said or read

biologist

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US / baɪˈɒlədʒɪst /

UK / baɪˈɑːlədʒɪst /

A2
  • noun
  • A scientist who studies living things

whenever

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US / wenˈevə(r) /

UK / hwɛnˈɛvɚ /

A1
  • adverb
  • At any or every time that

degradation

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US / ˌdegrəˈdeɪʃn /

UK / ˌdɛɡrəˈdeʃən /

B2
  • noun
  • Reduction in quality or character
  • Act of treating someone without respect

interesting

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US / ˈɪntrəstɪŋ /

UK / ˈɪntrɪstɪŋ, -tərɪstɪŋ, -təˌrɛstɪŋ /

A1
  • adjecitve
  • Taking your attention; making you want to know
  • verb
  • To make someone want to know about something
  • To persuade to do, become involved with something

dimensional

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US / dɪ'menʃənəl /

UK / dɪˈmɛnʃənl: /

B1
  • adjecitve
  • Concerning how many planes an object exists in

hit

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US / hɪt /

UK / hɪt /

A1
  • noun
  • A planned killing, usually for money
  • Song, movie etc. that is successful
  • When someone strikes someone or something
  • Time when a player makes contact with the ball
  • Time when a website is accessed
  • verb
  • To have a negative impact on a person/place/thing
  • To press something, such as a button or switch
  • To suddenly realize the importance of something
  • To move your hand, a bat, etc. against with force
  • To fight, attack or damage something or someone
  • To arrive at a specific place, level, or goal
  • To make contact with the ball in a game or sport

specie

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US / 'spi:ʃi: /

UK / 'spi:ʃɪ /

B1
  • noun
  • Singular of species

purple

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US / 'pɜ:pl /

UK / ˈpɚpəl /

A1
  • adjecitve
  • Being a color that is a mixture of red and blue

right

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US / raɪt /

UK / raɪt /

A1
  • adjecitve
  • Correct or true
  • The south side of you looking at the rising sun
  • adverb
  • Exactly in a place or time
  • Being appropriate for a particular event
  • In a straight or direct manner
  • noun
  • Something you are legally or morally allowed to do
  • Ideal of what is just and good
  • Political view based on conservatism
  • verb
  • To fix something previously wrong or unjust
  • To make upright, as a boat that has turned over

bend

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US / bend /

UK / bɛnd /

A2
  • noun
  • When a road changes direction; turn
  • verb
  • To become curved or no longer straight
  • To move your body so that it is not straight up
  • To turn in a different direction, as a road
  • To use force to make an object not straight

case

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US / keɪs /

UK / kes /

A1
  • noun
  • Container used to carry things, e.g. clothes
  • Set of facts about a crime
  • Set of facts about an event
  • Example or instance of something
  • verb
  • To find out about a place, as in planning to steal

anyone

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US / ˈeniwʌn /

UK / ˈɛniˌwʌn, -wən /

A1
  • pronoun
  • Any person

find

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US / faɪnd /

UK / faɪnd /

A1
  • noun
  • Object discovered by chance
  • Things that have been discovered from searching
  • verb
  • To become aware of something that is happening
  • To discover or meet by chance
  • To decide if someone is guilty of a crime, or not
  • To learn through study, research, or effort
  • To discover something by looking for it

flood

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US / flʌd /

UK / flʌd /

B1
  • noun
  • Large number of people or things arriving at once
  • Destruction when a river breaks its banks
  • verb
  • To quickly appear unexpectedly and in volume
  • (Of liquid) to fill or cover something completely

great

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US / ɡreɪt /

UK / ɡret /

A1
  • adjecitve
  • Very large in size
  • Very important
  • Very good; fantastic; wonderful
  • adverb
  • Very good; better than before
  • noun
  • Successful and well-admired person

lab

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US / læb /

UK / læb /

B1
  • noun
  • Short for 'laboratory'

mean

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US / mi:n /

UK / min /

A1
  • adjecitve
  • Being good at
  • Nasty; unkind
  • Not liking to spend money; cheap; stingy
  • noun
  • Average of a set of numbers
  • verb
  • To express a particular idea or thought
  • To intend to do something in particular
  • To have a particular meaning or value

oxygen

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US / 'ɒksɪdʒən /

UK / ˈɑksɪdʒən /

B1
  • noun
  • A gas in the air that we need to breathe

type

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US / taɪp /

UK / taɪp /

A1
  • noun
  • Printed letters or blocks used for printing them
  • Group of things or people sharing common features
  • verb
  • To identify something belonging to a group
  • To write by touching keys on a keyboard

again

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US / ə'ɡen /

UK / əˈɡɛn /

A1
  • adverb
  • One more time, once more

about

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US / ə'baʊt /

UK / əˈbaʊt /

A1
  • adverb
  • To be ready to; going to
  • Nearly; approximately; roughly
  • Near; next to; close to
  • In every direction; in the area of
  • preposition
  • Concerning or of (a topic)

even

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US / 'i:vn /

UK / ˈivən /

A1
  • adjecitve
  • Being equal in influence, power, possibility etc.
  • Being divided equally or fairly
  • (Of teams/contest) with similar chances of success
  • Smooth, level, or regular
  • Can be divided by 2; ending in 2, 4, 6, 8, or 0
  • At a regular, equally steady manner
  • Remaining steady and unchanging
  • adverb
  • (When this is surprising) as well; too
  • (Used to compare two things/stress the difference)
  • verb
  • To make something level; to flatten
  • To make something equal

different

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US / ˈdɪfrənt /

UK / ˈdɪfrənt /

A1
  • adjecitve
  • Not of the same kind; unlike other things

dimensionality

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US / dɪˌmenʃə'nælɪtɪ /

UK / dɪˌmenʃə'nælətɪ /

A1
  • other
  • The spatial property of having dimensions

like

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US / laɪk /

UK / laɪk /

A1
  • adjecitve
  • Being equal in status or kind to something else
  • Similar; the same
  • adverb
  • For example
  • preposition
  • Used as a filler; used to ad emphasis
  • In a way similar to the way something is done
  • Such as; for example
  • verb
  • To want to
  • To find something pleasing; to prefer something

reaction

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US / rɪ'ækʃn /

UK / riˈækʃən /

A2
  • noun
  • Bodily response to a drug or something eaten
  • Feeling or action in response to something

that

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US / ðæt /

UK / ðæt, ðət /

A1
  • adjecitve
  • The person or thing being talked about
  • Used to identify something both the speakers know
  • adverb
  • Used to reinforce adjectives and adverbs
  • To such a degree
  • conjunction
  • Used to connect a noun clause
  • Used to introduce an adverbial clause
  • Used to introduce a noun clause
  • determiner
  • Used as a noun to refer to something
  • pronoun
  • Referring an object far away
  • Used to refer to the relative pronoun ‘which’

site

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US / saɪt /

UK / saɪt /

A2
  • noun
  • Place that is reserved for a particular activity
  • Location of building work
  • Location of something
  • Place where something of special interest happened
  • Website
  • verb
  • To place something in a particular position, area

what

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US / wɒt /

UK / hwɑt, hwʌt, wɔt, wʌt,hwət, wət /

A1
  • pronoun
  • Thing or things that; the same kind as
  • Used to emphasize something you are about to say
  • adjecitve
  • Used to refer to a particular amount, or number
  • Used to place emphasis on a particular quality
  • adverb
  • To a certain degree
  • determiner
  • Question words used for asking for information
  • exclamation
  • Used to express excitement, shock, or surprise
  • Used to ask people to repeat something they said

week

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US / wi:k /

UK / wik /

A1
  • noun
  • Period of seven days from Sunday to Saturday

example

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US / ɪgˈzɑ:mpl /

UK / ɪɡˈzæmpəl /

A1
  • noun
  • Thing, person which represents a category

typical

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US / ˈtɪpɪkl /

UK / ˈtɪpɪkəl /

A2
  • adjecitve
  • Normal; usual; expected

virtual

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US / ˈvɜ:tʃuəl /

UK / ˈvɚtʃuəl /

B1
  • adjecitve
  • Existing only on the internet or on a computer
  • Existing only in a digital world
  • Almost being; nearly complete
  • Subtitles section
  • One of my favourite quotes or phrases is by Charles Mingos, who's a jazz musician, who said anyone can make the simple complicated.
  • Creativity is making the complicated simple.
  • So what we're doing is trying to make complicated looking molecules in the most simple way that you can.
  • Okay, well this is one of my latest papers.
  • I'm very excited about this project at the moment.
  • A bit of a mouthful actually.
  • Synthesis of natural product like scaffolds in unprecedented efficiency via 12-fold branching pathways.
  • I'm going to try and explain to you what I mean by that, because that's a bit of a mouthful like I say.
  • And this is going to make it simple?
  • Hopefully, hopefully.
  • There's a lot of complexity here, but this is what we're talking about.
  • Well the reason first that we did this work is that over the years the pharmaceutical industry has provided many interesting compounds which now treat illness and disease.
  • This is a typical compound, it's an anti-hypertensive agent.
  • What does that mean?
  • It's a sedative to you and me.
  • The key feature of this is it's pretty flat.
  • It's not a lot of three dimensionality in this molecule.
  • And a few studies over the last couple of years have shown that actually more three dimensionality in a drug candidate can lead to more success.
  • And of course receptors that these guys hit, they're all three dimensionally shaped.
  • You can think of them like a cave.
  • And these guys when they go in, they obviously fit in key sites, certain interactions.
  • But if you can fill in a bit of the space around, maybe you can get better selectivity and less oxidation and other types of degradation.
  • What you're looking at here, there's a whole range of molecules, all of which are quite interesting looking three dimensional shapes.
  • You can see there's definite three dimensionality here and here.
  • And all of these molecules are made in a single step from this molecule here.
  • This very simple linear looking molecule is the precursor to all of those.
  • They all take one step.
  • Here we have two ester groups at the end, over here.
  • And we've got a simple ketone in the middle.
  • And this is just a chain connecting these two side chains.
  • And what's that thing called, that thing you're holding?
  • Has it got a name, that molecule?
  • It has 6-ketoandecadienedione, diethyl ester.
  • Or the keto diester, as we like to call it.
  • So this is the magic precursor.
  • It's going to wrap itself up and make all of these complex shapes.
  • And you think, look at the difference between that simple molecule there and this really complicated architecture over here.
  • That's just one chemical reaction that's done that.
  • So the analogy is a piece of string.
  • Here is our piece of string, this molecule here.
  • Now if we can take a piece of string or a rope and we can tie this up into a knot.
  • Big fingers are great for glassware, you never drop anything.
  • Not so good for little intricate things like that.
  • So there you see we've made a three-dimensional shape from a linear shape.
  • If you take a much bigger bit of string, you can get a more intricate looking knot.
  • And that's what we're doing with this molecule here.
  • So what we do is we take this central functionality, the ketone in the middle, and we can convert that into a whole range of different species.
  • So in this case, I'm just going to take that off.
  • There goes the oxygen.
  • We do a condensation reaction with a hydroxylamine.
  • That's an amine and an oxygen.
  • And what this can do is this can now react with one of these alkenes and that forms a ring.
  • And this oxygen here and this carbon, this functionality now is something we call a nitrone.
  • That's now going to react like so and it just ties around in a knot.
  • And we've just made one of these molecules here, that one there.
  • So we've just made that molecule there from that linear molecule.
  • And that's what we've done.
  • We've found 12 different so-called tandem reactions.
  • So this tying up in a knot is something called a tandem reaction.
  • It's where you make more than one bond in the same time.
  • In fact, in this case, we're making this bond here, this bond here, this bond here, and this bond here.
  • So we've made all those bonds, four bonds, in one chemical reaction.
  • And that's just tied the whole molecule up.
  • What we've done here is we've created a very simple way of making a whole variety of different three-dimensional molecules.
  • They look very different even though they come from the same precursor.
  • And traditionally, it may have taken 10, 15, 20 steps to make something like this.
  • Which, in terms of me in the lab, that could be three or four weeks if everything went to plan.
  • Now, all of these were produced in an average of just 1.25 steps per molecule, per compound, per architecture or scaffold, as the pharmaceutical industry would call them.
  • But how has what you've made, how has the things you've made, how are these useful though?
  • What use are they to the world?
  • You make them efficiently, but what good are they?
  • Right, so that's a great question.
  • So then the newest way of doing pharmaceutical research, trying to figure out where we can get our new generation of active compounds, is called something called fragment-based drug discovery.
  • So in this, we get the receptor, which is part of an enzyme.
  • And using X-ray crystallography, we can get a good map of the cave, if you like, of the receptor site.
  • And we can do virtual docking with computers.
  • We generate the shapes of these in the computers and the computer can dock it in and see if it fits and see if any interactions come off these key functionalities.
  • And also, with this type of screening, if we can get an enzyme which we can get an X-ray structure of, then we can flood it with a whole variety of these molecules and actually get an X-ray of these inside.
  • And what the pharmaceutical industry needs is smallish molecules of defined three-dimensional shape with things like these purple groups here, which I've just put on, because you can change these groups into huge loads of other different types of groups.
  • So these are really useful functional handles.
  • And the majority of them, I have to say, came out as we hoped, and it was great.
  • The occasional one, like this one for example, chemistry just came along and surprised us a little bit.
  • We thought that this would bend around and actually attach over here as well, and it turned out it didn't want to do that.
  • So you occasionally get surprises, which are great.
  • Huge scientific breakthroughs have been made through complete serendipity or surprise or luck.
  • And we always want to encourage luck whenever we can find it.
  • Others, like this one here, we designed completely the tandem reaction.
  • We were really pleased when it came out and it worked, and we made this.
  • So this molecule here is this sample over here.
  • Now we've not got very much in this sample.
  • We've taken a lot of these and sent them away to biologists, but there's about 0.1 of a gram in here.
  • So this is this one here.
  • This one's a slightly lighter colour, and again, it depends on what we do with these over here.
  • It's not complicated at all.
  • It's all about imagination, and it's all about creativity.